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Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/study/NCT02280551




Registration number
NCT02280551
Ethics application status
Date submitted
29/10/2014
Date registered
31/10/2014
Date last updated
6/05/2021

Titles & IDs
Public title
The Australian Parental Supply of Alcohol Longitudinal Study (APSALS)
Scientific title
The Australian Parental Supply of Alcohol Longitudinal Study (APSALS)
Secondary ID [1] 0 0
DP:1096668
Universal Trial Number (UTN)
Trial acronym
APSALS
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Alcohol Abuse 0 0
Condition category
Condition code
Mental Health 0 0 0 0
Addiction

Intervention/exposure
Study type
Observational
Patient registry
Target follow-up duration
Target follow-up type
Description of intervention(s) / exposure
Adolescents - 1927 Grade 7 high school students

Parent - A parent of each of the 1927 Grade 7 high school students
Comparator / control treatment
Control group

Outcomes
Primary outcome [1] 0 0
Frequency of alcohol consumption
Timepoint [1] 0 0
12 month
Primary outcome [2] 0 0
Typical quantity of alcohol consumption
Timepoint [2] 0 0
12 month
Primary outcome [3] 0 0
Frequency of binge drinking
Timepoint [3] 0 0
12 month
Primary outcome [4] 0 0
Experience of alcohol related harms
Timepoint [4] 0 0
12 months
Primary outcome [5] 0 0
Symptoms of alcohol abuse, dependence and alcohol use disorder
Timepoint [5] 0 0
12 months

Eligibility
Key inclusion criteria
* Grade 7 High School enrolment
* Parental signed informed consent provided
Minimum age
11 Years
Maximum age
13 Years
Sex
Both males and females
Can healthy volunteers participate?
Yes
Key exclusion criteria
* none

Study design
Purpose
Duration
Selection
Timing
Prospective
Statistical methods / analysis

Recruitment
Recruitment status
UNKNOWN
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Anticipated
Actual
1/03/2010
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
1/12/2021
Actual
Sample size
Target
Accrual to date
Final
1927
Recruitment in Australia
Recruitment state(s)
NSW
Recruitment hospital [1] 0 0
University of New South Wales - Sydney
Recruitment postcode(s) [1] 0 0
2052 - Sydney

Funding & Sponsors
Primary sponsor type
Other
Name
The University of New South Wales
Address
Country

Ethics approval
Ethics application status

Summary
Brief summary
Parents can positively influence their children's alcohol use. One strategy they use is to provide their children with alcohol, believing it is the best way to teach their children how to drink responsibly. The impact of parental supply is not well understood and may be unintentionally harmful. This study will research the consequences of parental supply within the broader context of parent, child and peer relationships. It will help to determine how parental supply influences the different patterns of adolescent alcohol consumption over time, providing essential information to help parents prevent alcohol misuse in their children. Parents can play a pivotal role in prevention of alcohol misuse, but at present we don't know exactly how.
Trial website
https://clinicaltrials.gov/study/NCT02280551
Trial related presentations / publications
Wadolowski M, Bruno R, Aiken A, Stone C, Najman J, Kypri K, Slade T, Hutchinson D, McBride N, Mattick RP. Sipping, drinking, and early adolescent alcohol consumption: a cautionary note. Alcohol Clin Exp Res. 2015 Feb;39(2):350-4. doi: 10.1111/acer.12613.
Wadolowski M, Hutchinson D, Bruno R, Aiken A, Clare P, Slade T, Najman J, Kypri K, McBride N, Mattick RP. Early Adolescent Alcohol Use: Are Sipping and Drinking Distinct? Alcohol Clin Exp Res. 2015 Sep;39(9):1805-13. doi: 10.1111/acer.12826. Epub 2015 Aug 6.
Wadolowski M, Hutchinson D, Bruno R, Aiken A, Najman JM, Kypri K, Slade T, McBride N, Mattick RP. Parents Who Supply Sips of Alcohol in Early Adolescence: A Prospective Study of Risk Factors. Pediatrics. 2016 Mar;137(3):e20152611. doi: 10.1542/peds.2015-2611. Epub 2016 Feb 26.
Mattick RP, Wadolowski M, Aiken A, Clare PJ, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K. Parental supply of alcohol and alcohol consumption in adolescence: prospective cohort study. Psychol Med. 2017 Jan;47(2):267-278. doi: 10.1017/S0033291716002373. Epub 2016 Oct 5.
Aiken A, Wadolowski M, Bruno R, Najman J, Kypri K, Slade T, Hutchinson D, McBride N, Mattick RP. Cohort Profile: The Australian Parental Supply of Alcohol Longitudinal Study (APSALS). Int J Epidemiol. 2017 Apr 1;46(2):e6. doi: 10.1093/ije/dyv051.
Aiken A, Clare PJ, Wadolowski M, Hutchinson D, Najman JM, Slade T, Bruno R, McBride N, Kypri K, Mattick RP. Age of Alcohol Initiation and Progression to Binge Drinking in Adolescence: A Prospective Cohort Study. Alcohol Clin Exp Res. 2018 Jan;42(1):100-110. doi: 10.1111/acer.13525. Epub 2017 Nov 21.
Mattick RP, Clare PJ, Aiken A, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Kypri K, Vogl L, Degenhardt L. Association of parental supply of alcohol with adolescent drinking, alcohol-related harms, and alcohol use disorder symptoms: a prospective cohort study. Lancet Public Health. 2018 Feb;3(2):e64-e71. doi: 10.1016/S2468-2667(17)30240-2. Epub 2018 Feb 1. Erratum In: Lancet Public Health. 2018 Mar;3(3):e114. doi: 10.1016/S2468-2667(18)30023-9.
Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam M, Aiken A, Hutchinson D, M Najman J, Slade T, McBride N, Attia J, P Mattick R. Parent characteristics associated with approval of their children drinking alcohol from ages 13 to 16 years: prospective cohort study. Aust N Z J Public Health. 2018 Aug;42(4):347-353. doi: 10.1111/1753-6405.12811. Epub 2018 Jul 23.
Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam M, Aiken A, Hutchinson D, Najman JM, Slade T, McBride N, Attia J, Palazzi K, Oldmeadow C, Mattick RP. Parent hazardous drinking and their children's alcohol use in early and mid-adolescence: prospective cohort study. Eur J Public Health. 2019 Aug 1;29(4):736-740. doi: 10.1093/eurpub/ckz029.
Clare PJ, Aiken A, Yuen WS, Peacock A, Boland V, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K, Mattick RP. Parental supply of alcohol as a predictor of adolescent alcohol consumption patterns: A prospective cohort. Drug Alcohol Depend. 2019 Nov 1;204:107529. doi: 10.1016/j.drugalcdep.2019.06.031. Epub 2019 Aug 29.
Clare PJ, Dobbins T, Bruno R, Peacock A, Boland V, Yuen WS, Aiken A, Degenhardt L, Kypri K, Slade T, Hutchinson D, Najman JM, McBride N, Horwood J, McCambridge J, Mattick RP. The overall effect of parental supply of alcohol across adolescence on alcohol-related harms in early adulthood-a prospective cohort study. Addiction. 2020 Oct;115(10):1833-1843. doi: 10.1111/add.15005. Epub 2020 Mar 6.
Boland VC, Clare PJ, Yuen WS, Peacock A, Aiken A, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K, Mattick RP. The association between parental supply of alcohol and supply from other sources to young people: a prospective cohort. Addiction. 2020 Nov;115(11):2140-2147. doi: 10.1111/add.15033. Epub 2020 Mar 24.
Yuen WS, Chan G, Bruno R, Clare P, Mattick R, Aiken A, Boland V, McBride N, McCambridge J, Slade T, Kypri K, Horwood J, Hutchinson D, Najman J, De Torres C, Peacock A. Adolescent Alcohol Use Trajectories: Risk Factors and Adult Outcomes. Pediatrics. 2020 Oct;146(4):e20200440. doi: 10.1542/peds.2020-0440. Epub 2020 Sep 23.
Aiken A, Clare PJ, Boland VC, Degenhardt L, Yuen WS, Hutchinson D, Najman J, McCambridge J, Slade T, McBride N, De Torres C, Wadolowski M, Bruno R, Kypri K, Mattick RP, Peacock A. Parental supply of sips and whole drinks of alcohol to adolescents and associations with binge drinking and alcohol-related harms: A prospective cohort study. Drug Alcohol Depend. 2020 Oct 1;215:108204. doi: 10.1016/j.drugalcdep.2020.108204. Epub 2020 Aug 5.
Yuen WS, Chan G, Bruno R, Clare PJ, Aiken A, Mattick R, Farrell M, Kypri K, Slade T, Hutchinson D, McBride N, McCambridge J, Boland V, Peacock A. Trajectories of alcohol-induced blackouts in adolescence: early risk factors and alcohol use disorder outcomes in early adulthood. Addiction. 2021 Aug;116(8):2039-2048. doi: 10.1111/add.15415. Epub 2021 Feb 1.
Aiken A, Chan G, Yuen WS, Clare PJ, Hutchinson D, McBride N, Najman JM, McCambridge J, Upton E, Slade T, Boland VC, De Torres C, Bruno R, Kypri K, Wadolowski M, Mattick RP, Peacock A. Trajectories of parental and peer supply of alcohol in adolescence and associations with later alcohol consumption and harms: A prospective cohort study. Drug Alcohol Depend. 2022 Aug 1;237:109533. doi: 10.1016/j.drugalcdep.2022.109533. Epub 2022 Jun 11.
Najman JM, Clare PJ, Kypri K, Aiken A, Wadolowski M, Hutchinson D, Slade T, Bruno R, Vogl L, Degenhardt L, Mattick RP. Gender differences in the supply of alcohol to adolescent daughters and sons. Am J Drug Alcohol Abuse. 2021 Jul 4;47(4):508-520. doi: 10.1080/00952990.2021.1927066. Epub 2021 Aug 12.
Public notes

Contacts
Principal investigator
Name 0 0
RICHARD P MATTICK, PhD
Address 0 0
NATIONAL DRUG AND ALCOHOL RESEARCH CENTRE, UNSW AUSTRALIA
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries



Summary Results

For IPD and results data, please see https://clinicaltrials.gov/study/NCT02280551